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As the market anticipates maintenance data in 2026, the key focus will be on how clinicians value this unique mechanism against the familiarity and perceived potency of emerging oral IL-23 inhibitors

If retatrutide is approved in the future, that conversation can be had at the point of approval, when the safety profile and access pathway are clearer

Incorporate gentle movement It might seem counterintuitive when you're tired, but light physical activity can actually improve energy levels

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Some patients report feeling less energetic during the initial months of treatment, with gradual improvement as weight stabilizes and metabolic adaptation occurs

Important Safety Considerations Before you decide to change your injection timing, there are several safety factors to keep in mind