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Entering clinical trials in 2013, a phase 2 study published in 2018 showed significant and dose-dependent reductions in glycated hemoglobin (HbA1c) in Chinese patients with T2D 3

High-risk patients need tailored precautions

doi: 10.1016/s0014-2999(96)00663-2

In a study of transgenic mice with a Kras G12D mutation which induces PanINs and eventually pancreatic cancer, treatment with exendin-4 increased higher grade PanIN lesions (35, 38)

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