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GLP-1R agonists have shown potential benefits in muscle health by decreasing muscle atrophy and inflammation, as well as improving muscle microvasculature and endurance (68)

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Spencer Nadolsky, an obesity doctor who has dug into this, keeps making both points at once: the loss is about what youd expect from any calorie deficit, and better imaging that separates real muscle from water and fat shows the scan numbers were overstated